A Big 12 battle is on tap between the No. 23 Iowa State Cyclones and the West Virginia Mountaineers at 9 p.m. ET on Monday at James H. Hilton Coliseum. Iowa State has lost five of its last six games, including a 76-71 loss to West Virginia on Feb. 8.  The Cyclones are favored by 4 points in the latest Iowa State vs. West Virginia odds from Caesars Sportsbook, while the over/under is set at 134. 

Before you make any West Virginia vs. Iowa State picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 17 of the season 76-46 on all-top rated college basketball picks this season, returning more than $1,600 for $100 players. Anybody who has followed it has seen HUGE returns. 

Now, it has simulated Iowa State vs. West Virginia 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Iowa State vs. West Virginia? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!